1,392 research outputs found

    Assentication: User Deauthentication and Lunchtime Attack Mitigation with Seated Posture Biometric

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    Biometric techniques are often used as an extra security factor in authenticating human users. Numerous biometrics have been proposed and evaluated, each with its own set of benefits and pitfalls. Static biometrics (such as fingerprints) are geared for discrete operation, to identify users, which typically involves some user burden. Meanwhile, behavioral biometrics (such as keystroke dynamics) are well suited for continuous, and sometimes more unobtrusive, operation. One important application domain for biometrics is deauthentication, a means of quickly detecting absence of a previously authenticated user and immediately terminating that user's active secure sessions. Deauthentication is crucial for mitigating so called Lunchtime Attacks, whereby an insider adversary takes over (before any inactivity timeout kicks in) authenticated state of a careless user who walks away from her computer. Motivated primarily by the need for an unobtrusive and continuous biometric to support effective deauthentication, we introduce PoPa, a new hybrid biometric based on a human user's seated posture pattern. PoPa captures a unique combination of physiological and behavioral traits. We describe a low cost fully functioning prototype that involves an office chair instrumented with 16 tiny pressure sensors. We also explore (via user experiments) how PoPa can be used in a typical workplace to provide continuous authentication (and deauthentication) of users. We experimentally assess viability of PoPa in terms of uniqueness by collecting and evaluating posture patterns of a cohort of users. Results show that PoPa exhibits very low false positive, and even lower false negative, rates. In particular, users can be identified with, on average, 91.0% accuracy. Finally, we compare pros and cons of PoPa with those of several prominent biometric based deauthentication techniques

    Perspectives on the insidious nature of pain metaphor: we literally need to change our metaphors.

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    Metaphorical language is used to convey one thing as representative or symbolic of something else. Metaphor is used in figurative language but is much more than a means of delivering "poetic imagination". A metaphor is a conceptual tool for categorising, organizing, thinking about, and ultimately shaping reality. Thus, metaphor underpins the way humans think. Our viewpoint is that metaphorical thought and communication contribute to "painogenicity", the tendency of socio-ecological environments (settings) to promote the persistence of pain. In this perspectives article, we explore the insidious nature of metaphor used in pain language and conceptual models of pain. We explain how metaphor shapes mental organisation to govern the way humans perceive, navigate and gain insight into the nature of the world, i.e., creating experience. We explain how people use metaphors to "project" their private sensations, feelings, and thoughts onto objects and events in the external world. This helps people to understand their pain and promotes sharing of pain experience with others, including health care professionals. We explore the insidious nature of "warmongering" and damage-based metaphors in daily parlance and demonstrate how this is detrimental to health and wellbeing. We explore how metaphors shape the development and communication of complex, abstract ideas, theories, and models and how scientific understanding of pain is metaphorical in nature. We argue that overly simplistic neuro-mechanistic metaphors of pain contribute to fallacies and misnomers and an unhealthy focus on biomedical research, in the hope of developing medical interventions that "prevent pain transmission [sic]". We advocate reconfiguring pain language towards constructive metaphors that foster a salutogenic view of pain, focusing on health and well-being. We advocate reconfiguring metaphors to align with contemporary pain science, to encourage acceptance of non-medicalised strategies to aid health and well-being. We explore the role of enactive metaphors to facilitate reconfiguration. We conclude that being cognisant of the pervasive nature of metaphors will assist progress toward a more coherent conceptual understanding of pain and the use of healthier pain language. We hope our article catalyses debate and reflection

    Dilemmas in doing insider research in professional education

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    This article explores the dilemmas I encountered when researching social work education in England as an insider researcher who was simultaneously employed as an educator in the host institution. This was an ethnographic project deploying multiple methods and generating rich case study material which informed the student textbook Becoming a Social Worker the four-year period of the project. First, ethical dilemmas emerged around informed consent and confidentiality when conducting surveys of students and reading their portfolios. Second, professional dilemmas stemmed from the ways in which my roles as a researcher, academic tutor, social worker and former practice educator converged and collided. Third, political dilemmas pertained to the potential for the project to crystallize and convey conflicts among stakeholders in the university and community. Since the majority of research in social work education is conducted by insiders, we have a vital interest in making sense of such complexity

    Detection of Genetically Altered Copper Levels in Drosophila Tissues by Synchrotron X-Ray Fluorescence Microscopy

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    Tissue-specific manipulation of known copper transport genes in Drosophila tissues results in phenotypes that are presumably due to an alteration in copper levels in the targeted cells. However direct confirmation of this has to date been technically challenging. Measures of cellular copper content such as expression levels of copper-responsive genes or cuproenzyme activity levels, while useful, are indirect. First-generation copper-sensitive fluorophores show promise but currently lack the sensitivity required to detect subtle changes in copper levels. Moreover such techniques do not provide information regarding other relevant biometals such as zinc or iron. Traditional techniques for measuring elemental composition such as inductively coupled plasma mass spectroscopy are not sensitive enough for use with the small tissue amounts available in Drosophila research. Here we present synchrotron x-ray fluorescence microscopy analysis of two different Drosophila tissues, the larval wing imaginal disc, and sectioned adult fly heads and show that this technique can be used to detect changes in tissue copper levels caused by targeted manipulation of known copper homeostasis genes

    Maternal concentration of polychlorinated biphenyls and dichlorodiphenyl dichlorethylene and birth weight in Michigan fish eaters: a cohort study

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    BACKGROUND: Studies on maternal exposure to polychlorinated biphenyls (PCBs) reported inconsistent findings regarding birth weight: some studies showed no effect, some reported decreased birth weight, and one study found an increase in weights. These studies used different markers of exposure, such as measurement of PCBs in maternal serum or questionnaire data on fish consumption. Additionally maternal exposures, such as dichlorodiphenyl-dichloroethylene (DDE), which are related to PCB exposure and may interfere with the PCB effect, were rarely taken into account. METHODS: Between 1973 and 1991, the Michigan Department of Community Health conducted three surveys to assess PCB and DDE serum concentrations in Michigan anglers. Through telephone interviews with parents, we gathered information on the birth characteristics of their offspring, focusing on deliveries that occurred after 1968. We used the maternal organochlorine (OC) measurement closest to the date of delivery as the exposure. Although one mother may have contributed more than one child, serum concentrations derived from measurements in different surveys could vary for different children from the same mother. The maternal DDE and PCB serum concentrations were categorized as follows: 0 -< 5 microg / L, 5 -< 15 microg / L, 15 -< 25 microg / L, ≥25 microg / L. Using repeated measurement models (Generalized Estimation Equation), we estimated the adjusted mean birth weight controlling for gender, birth order, gestational age, date of delivery as well as maternal age, height, education, and smoking status. RESULTS: We identified 168 offspring who were born after 1968 and had maternal exposure information. We found a reduced birth weight for the offspring of mothers who had a PCB concentration ≥25 microg / L (adjusted birth weight = 2,958 g, p = 0.022). This group, however, was comprised of only seven observations. The association was not reduced when we excluded preterm deliveries. The birth weight of offspring was increased in women with higher DDE concentrations when controlling for PCBs; however, this association was not statistically significant. CONCLUSION: Our results contribute to the body of evidence that high maternal serum PCB concentration may reduce the birth weight in offspring. However, only a small proportion of mothers may actually be exposed to PCB concentrations ≥25 microg / L

    Fast X-Ray Fluorescence Microtomography of Hydrated Biological Samples

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    Metals and metalloids play a key role in plant and other biological systems as some of them are essential to living organisms and all can be toxic at high concentrations. It is therefore important to understand how they are accumulated, complexed and transported within plants. In situ imaging of metal distribution at physiological relevant concentrations in highly hydrated biological systems is technically challenging. In the case of roots, this is mainly due to the possibility of artifacts arising during sample preparation such as cross sectioning. Synchrotron x-ray fluorescence microtomography has been used to obtain virtual cross sections of elemental distributions. However, traditionally this technique requires long data acquisition times. This has prohibited its application to highly hydrated biological samples which suffer both radiation damage and dehydration during extended analysis. However, recent advances in fast detectors coupled with powerful data acquisition approaches and suitable sample preparation methods can circumvent this problem. We demonstrate the heightened potential of this technique by imaging the distribution of nickel and zinc in hydrated plant roots. Although 3D tomography was still impeded by radiation damage, we successfully collected 2D tomograms of hydrated plant roots exposed to environmentally relevant metal concentrations for short periods of time. To our knowledge, this is the first published example of the possibilities offered by a new generation of fast fluorescence detectors to investigate metal and metalloid distribution in radiation-sensitive, biological samples

    Microspectroscopy beamline at the Australian synchrotron: design and capabilities.

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    A hard x-ray micro-nanoprobe is being constructed at the Australian Synchrotron [1] to provide sub-micron spatial resolution across an energy range of 4.5–25 keV. The SXM will combine 2D mapping with μ-XRF, μ-XANES and μ-XAFS for elemental and chemical microanalysis. The primary design goal is to achieve sub-100 nm spatial resolution with DE/E ~10-4, and sub-ppm elemental sensitivity. The optical design is a novel “all horizontal” scheme [2]. Interchangeable Fresnel zone plates and Kirkpatrick-Baez mirrors will be used. An advanced fluorescence detector developed by BNL [3] and CSIRO [4] featuring a large solid-angle planar silicon array will enable count rates up to 108 events/sec and real-time processing with deconvoluted image projection. A differential phase contrast detection scheme [5] will be employed for quantitative measurement of soft matter [6]. The Microspectroscopy Beamline will commence operation in late 2008 and will accommodate a diverse range of environmental, biological and materials science applications to cater for the broad requirements of the Australian community. The design, anticipated performance and research applications will be discussed.Paul Scherrer Institut (PSI
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